![]() Additionally, at week 52, histochemical data confirmed the clinical results, showing increased expression of type I procollagen, hyaluronan, and Ki67 as compared to vehicleĬONCLUSION: This study confirms that a stabilized retinol (0.1%) formulation can significantly improve the signs of photoaging, and improvements in photodamage continue with prolonged use. After 52 weeks, retinol had improved crow’s feet fine lines by 44%, and mottled pigmentation by 84%, with over 50% of subjects showing +2 grades of improvement in many parameters. RESULTS: The retinol group showed significant photodamage improvement over vehicle at all timepoints during the study. A second exploratory study evaluated histological/histochemical markers in 12 subjects after 52 weeks of either retinol or vehicle use on contralateral dorsal forearms. Looking for Laboratories Analytical & Testing near me in Broomall, PA Get info about Kgl Skin Study Center & similar nearby companies offering Medical. Get KGL Skin Study Center reviews, ratings, business hours, phone numbers, and directions. KGL Skin Study Center can be contacted at (610) 544-1715. ![]() In the main study, 62 subjects applied either a stabilized retinol formulation or its vehicle to the full face. KGL Skin Study Center is located at 4699 West Chester Pike, Newtown Square, PA 19073. METHODS: The investigation included two 52-week, double-blind, vehicle-controlled studies. OBJECTIVE: This study aimed to assess the efficacy and safety of 0.1% stabilized retinol on photodamaged skin during a one-year treatment. AbstractBACKGROUND: Retinol, a precursor of retinoic acid, has great potentials as a topical anti-aging molecule however, only a handful of clinical investigations have been published to date.
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